The neo zeo rocks are supposed to be put in a reactor to control the flow through them when maintaining a tank with the neo zeo system. There are also specific doses of MB7 and Bio-Fuel to go along with the media, amount of media, flow suggestion and dosage of MB7 and RBF are in the instructions on the products. If I was dosing the MB7 into the main tank I would mix it in a cup of water before dumping it in, since I have a sump most of the time I just dump the dosage straight into my sump in the inflow area and let it dilute itself. I have had good luck with the neo zeo taking care of my nitrate and phosphates. I just use the MB7, RBF and stones, I didn't see any difference when I added in the CoralAmino or the Vit C in my tank.