I can't say I would make an acrylic tank and just use silicone, but the stuff sure as heck sticks like something I've never seen before. At one point I had just a small piece to go, I was pulling and yanking on it so hard to see if it would just pop off and no suck luck. I think I had a better chance at pulling the back wall of glass off that connects the sides before I could get this small piece of plastic/acrylic (whatever it is) off. I think i have cuts and scrapes on each finger, slice on my arm, and most likely some blood smeared in the tank somewhere. (Guess thats what I get for finishing it at 4:30 AM)....NEVER again will I attempt anything like that. I'll just buy a new tank.
I think that is what I'm going to do, just remove as much of the internal silicone as I can without bothering what connects the glass pieces together then put a nice thick coat all around just to be safe.