I am running a 30 gallon/10 gallon sump with a Rio 2800 SS (rated at 782 GPH) and the flow is strong, but with having two bulkheads for drainage and a nice return flow deflector I have no dead water zones nor need a powerhead in the tank, which gives a nice clean look. I use a filter sock in the sump and have a Remora AquaC skimmer powered by a Maxijet 1200 (rated at ~300 GPH). Thus, the tank turns ~19 times an hour using mechanical filtration and ~8 times through the skimmer...
Looks like the Rio 2500 is rated for 748 GPH, so 30 gallons + 10 gallon sump (guess) = 748 GPH / 40 Gallons = 18.7 Gallon turnover per hour...
I am new to the hobby, so I am not going to say I have great experience with this setup nor am I going to bless your setup, but thought I would share my configuration with you to see that it can be done.
My buddy ran this very setup for 4 years with success, so now it's my turn; 3 months and still working.